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工商注冊(cè)信息已核實(shí)!領(lǐng)域: | 化學(xué)藥,生物制藥/仿制藥,臨床血液與檢驗(yàn)學(xué) | ||
樣品: | 人血漿 | 項(xiàng)目: | 去氨加壓素 |
參考: | Neudert, L.; Zaugg, M.; Wood, S.; Struwe, P. A High Sensitivity Dual Solid Phase Extraction LC-MS/MS Assay for the Determination of the Therapeutic PeptideDesmopressin in Human Plasma |
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高選擇性和高精度的人血漿中去氨加壓素分析 |
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The results presented demonstrate the successful development of an accurate, precise, and selective SPE-LC-MS/MS method for the analysis of desmopressin from human plasma. Use of micro-elution SPE allowed for concentration of the sample prior to analysis without the need for post-extraction processing. Utilizing SOLAμ mixed-mode SPE provided both a clean and repeatable extract across the concentration range.
結(jié)果表明, 該方法成功地研制出了一種精確、精確、選擇性的 SPE-LC-MS/MS方法,用于分析人血漿中的去氨加壓。使用微洗脫SPE 可以濃縮樣品,在儀器分析前不需要后提取步驟。利用 SOLAμ混合模式 SPE,實(shí)現(xiàn)了在整個(gè)濃度范圍內(nèi)干凈、可重復(fù)性的提取。
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